| Game |
| Result | Moves |
Year |
Event/Locale | Opening |
| 1. Nisipeanu vs Y Kosashvili |
| 1-0 | 66 |
1998 |
Elista ol (Men) | C67 Ruy Lopez |
| 2. Nisipeanu vs I Nikolaidis |
| ½-½ | 21 |
1998 |
Elista ol (Men) | C92 Ruy Lopez, Closed |
| 3. Nisipeanu vs Azmaiparashvili |
| ½-½ | 44 |
1999 |
Ch World FIDE, Las Vegas (USA) | C60 Ruy Lopez |
| 4. Nisipeanu vs G Giorgadze |
| ½-½ | 29 |
1999 |
EU-chT (Men) | C87 Ruy Lopez |
| 5. Nisipeanu vs Onischuk |
| 0-1 | 44 |
2000 |
Cap d'Agde-B | C78 Ruy Lopez |
| 6. Nisipeanu vs Kiril Georgiev |
| ½-½ | 57 |
2000 |
FIDE World Ch | C67 Ruy Lopez |
| 7. Nisipeanu vs L Vajda |
| ½-½ | 37 |
2001 |
Victor Ciocaltea Mem | C90 Ruy Lopez, Closed |
| 8. Nisipeanu vs Kaidanov |
| ½-½ | 27 |
2002 |
Bled Olympiad | C78 Ruy Lopez |
| 9. Nisipeanu vs Kiril Georgiev |
| ½-½ | 27 |
2002 |
Bled Olympiad | C67 Ruy Lopez |
| 10. Nisipeanu vs Beliavsky |
| ½-½ | 33 |
2002 |
90th LSK Metalka Trgovina | C84 Ruy Lopez, Closed |
| 11. Nisipeanu vs Kasimdzhanov |
| ½-½ | 26 |
2003 |
Vlissingen HZ op | C89 Ruy Lopez, Marshall |
| 12. Nisipeanu vs M Sebag |
| 1-0 | 50 |
2003 |
7th Neckar Open | C68 Ruy Lopez, Exchange |
| 13. Nisipeanu vs A Rosmuller |
| 1-0 | 19 |
2003 |
HZ Open | C88 Ruy Lopez |
| 14. Nisipeanu vs R Hernandez |
 | 1-0 | 20 |
2003 |
XVI Carlos Torre Memorial KO | C69 Ruy Lopez, Exchange, Gligoric Variation, 6.d4 |
| 15. Nisipeanu vs Mamedyarov |
| ½-½ | 27 |
2004 |
FIDE World Championship Knockout Tournament | C87 Ruy Lopez |
| 16. Nisipeanu vs A Kunte |
| ½-½ | 9 |
2004 |
Pune Super GM | C67 Ruy Lopez |
| 17. Nisipeanu vs Mamedyarov |
| ½-½ | 30 |
2004 |
FIDE World Championship Knockout Tournament | C87 Ruy Lopez |
| 18. Nisipeanu vs Kasimdzhanov |
| ½-½ | 66 |
2004 |
Pune Super GM | C91 Ruy Lopez, Closed |
| 19. Nisipeanu vs Beliavsky |
| ½-½ | 32 |
2004 |
Pune Super GM | C89 Ruy Lopez, Marshall |
| 20. Nisipeanu vs Stefansson |
| ½-½ | 19 |
2004 |
36th Olympiad | C65 Ruy Lopez, Berlin Defense |
| 21. Nisipeanu vs Z Gyimesi |
| ½-½ | 63 |
2004 |
Bundesliga 0405 | C91 Ruy Lopez, Closed |
| 22. Nisipeanu vs Kasimdzhanov |
| ½-½ | 17 |
2005 |
BL 0506 Godesberger SK - SC Kreuzberg | C69 Ruy Lopez, Exchange, Gligoric Variation, 6.d4 |
| 23. Nisipeanu vs J Gustafsson |
| ½-½ | 36 |
2005 |
Bundesliga Final Weekend | C89 Ruy Lopez, Marshall |
| 24. Nisipeanu vs A Ivanov |
| 1-0 | 26 |
2005 |
Aeroflot Open | C91 Ruy Lopez, Closed |
| 25. Nisipeanu vs Delchev |
| 1-0 | 49 |
2006 |
15th CRO-ch team | C69 Ruy Lopez, Exchange, Gligoric Variation, 6.d4 |
