| Game |
| Result | Moves |
Year |
Event/Locale | Opening |
| 1. Karpov vs Kasparov |
 | ½-½ | 35 |
1986 |
Karpov-Kasparov World Championship Rematch | E60 King's Indian Defense |
| 2. Karpov vs Kasparov |
| ½-½ | 40 |
1986 |
Karpov-Kasparov World Championship Rematch | E60 King's Indian Defense |
| 3. Karpov vs Timman |
| 1-0 | 71 |
1986 |
Bugojno | E60 King's Indian Defense |
| 4. Karpov vs Kasparov |
| ½-½ | 30 |
1987 |
Karpov-Kasparov World Championship Match | E60 King's Indian Defense |
| 5. Karpov vs Timman |
| ½-½ | 57 |
1987 |
Karpov,A; Zaitsev,I, Amsterdam 43/576 | E60 King's Indian Defense |
| 6. Karpov vs Kasparov |
| ½-½ | 53 |
1987 |
Brussels | E60 King's Indian Defense |
| 7. Karpov vs Kasparov |
| ½-½ | 30 |
1987 |
Karpov-Kasparov World Championship Match | E60 King's Indian Defense |
| 8. Karpov vs Timman |
| 0-1 | 55 |
1987 |
Brussels 5' ;CBM 02 | E60 King's Indian Defense |
| 9. Karpov vs Kasparov |
| ½-½ | 37 |
1988 |
Karpov,A; Zaitsev,I | E60 King's Indian Defense |
| 10. Karpov vs Timman |
| ½-½ | 42 |
1990 |
m/2, Kuala Lumpur 49/519 [Timman,J | E60 King's Indian Defense |
| 11. Karpov vs Timman |
| 1-0 | 75 |
1990 |
Kuala Lumpur cf [Tischbierek u.a. | E60 King's Indian Defense |
| 12. Karpov vs Gelfand |
| 1-0 | 57 |
1991 |
Linares | E60 King's Indian Defense |
| 13. Karpov vs Kamsky |
| 1-0 | 54 |
1992 |
It (Alekhin's Memorial,cat.18) | E60 King's Indian Defense |
| 14. Karpov vs Timman |
| ½-½ | 51 |
1993 |
Karpov-Timman FIDE World Championship | E60 King's Indian Defense |
| 15. Karpov vs R Sheldon |
| ½-½ | 25 |
1994 |
25, ch-EU Disney Sim | E60 King's Indian Defense |
| 16. Karpov vs Gelfand |
| 1-0 | 50 |
1995 |
Sanghi Nagar IND | E60 King's Indian Defense |
| 17. Karpov vs Gelfand |
| ½-½ | 46 |
1995 |
Sanghi Nagar IND | E60 King's Indian Defense |
| 18. Karpov vs Glek |
| 1-0 | 50 |
1996 |
It (active), Cap D'Agde (France) | E60 King's Indian Defense |
| 19. Karpov vs Xiaomin Peng |
| ½-½ | 41 |
1998 |
Game (active), Beijing (China) | E60 King's Indian Defense |
| 20. Karpov vs Judit Polgar |
| ½-½ | 75 |
1998 |
Match (active), Budapest (Hungary) | E60 King's Indian Defense |
| 21. Karpov vs P Ricardi |
| 0-1 | 39 |
2000 |
Najdorf mem 11th | E60 King's Indian Defense |
| 22. Karpov vs Simeon Dimopoulos |
| 1-0 | 26 |
2001 |
Rethymno sim | E60 King's Indian Defense |
| 23. Karpov vs Ivanchuk |
| ½-½ | 39 |
2003 |
Wijk aan Zee | E60 King's Indian Defense |
| 24. Karpov vs Aronian |
| ½-½ | 59 |
2009 |
World Blitz Championship | E60 King's Indian Defense |
| 25. Karpov vs Svidler |
| ½-½ | 40 |
2009 |
ACP World Rapid Cup | E60 King's Indian Defense |
