| Game |
| Result | Moves |
Year |
Event/Locale | Opening |
| 1. Karpov vs O Dementiev |
 | 1-0 | 43 |
1971 |
07, Leningrad tt-army | D12 Queen's Gambit Declined Slav |
| 2. Karpov vs Portisch |
| 1-0 | 32 |
1975 |
Portoroz | D19 Queen's Gambit Declined Slav, Dutch |
| 3. Karpov vs Kupreichik |
| 1-0 | 42 |
1975 |
Latvia, Olympiad URS, Riga | D19 Queen's Gambit Declined Slav, Dutch |
| 4. Karpov vs Smyslov |
| 1-0 | 32 |
1981 |
cat. 15, It , Moscow | D11 Queen's Gambit Declined Slav |
| 5. Karpov vs Ljubojevic |
| ½-½ | 13 |
1983 |
518, Plovdiv 35/ | D11 Queen's Gambit Declined Slav |
| 6. Karpov vs Kasparov |
| ½-½ | 13 |
1984 |
Karpov-Kasparov World Championship Match | D11 Queen's Gambit Declined Slav |
| 7. Karpov vs Huebner |
| ½-½ | 61 |
1986 |
07, Tilburg ;CBM 03 | D19 Queen's Gambit Declined Slav, Dutch |
| 8. Karpov vs Gavrikov |
| 1-0 | 42 |
1988 |
Mazatlan | D15 Queen's Gambit Declined Slav |
| 9. Karpov vs V Tukmakov |
| 1-0 | 30 |
1988 |
active, It , Gijon (France) | D17 Queen's Gambit Declined Slav |
| 10. Karpov vs Huebner |
| ½-½ | 37 |
1988 |
Tilburg ;CBM 09 | D17 Queen's Gambit Declined Slav |
| 11. Karpov vs Ljubojevic |
| ½-½ | 79 |
1988 |
2nd Euwe Memorial | D11 Queen's Gambit Declined Slav |
| 12. Karpov vs Hjartarson |
| 1-0 | 42 |
1988 |
Tilburg 46/495 [Karpov,An; Zaitsev,I | D17 Queen's Gambit Declined Slav |
| 13. Karpov vs Timman |
| 1-0 | 41 |
1988 |
Tilburg 46/491 [Karpov,An; Zaitsev,I | D17 Queen's Gambit Declined Slav |
| 14. Karpov vs P Houtsonen |
| 1-0 | 13 |
1989 |
JYVASKYLA SIMULT. | D17 Queen's Gambit Declined Slav |
| 15. Karpov vs Ljubojevic |
| 0-1 | 50 |
1989 |
Rotterdam 47/460 [Karpov,An | D16 Queen's Gambit Declined Slav |
| 16. Karpov vs Mephisto |
| 0-1 | 83 |
1990 |
/- Munich | D16 Queen's Gambit Declined Slav |
| 17. Karpov vs Hort |
| ½-½ | 19 |
1990 |
Biel | D15 Queen's Gambit Declined Slav |
| 18. Karpov vs Salov |
| ½-½ | 30 |
1991 |
Linares 51/392 [Salov,V; Ionov,S | D19 Queen's Gambit Declined Slav, Dutch |
| 19. Karpov vs Bareev |
| 0-1 | 57 |
1992 |
Linares 54/354 [Bareev,E | D10 Queen's Gambit Declined Slav |
| 20. Karpov vs Yusupov |
| ½-½ | 61 |
1992 |
Alekhin's Memorial,cat.18, It , Moskva | D10 Queen's Gambit Declined Slav |
| 21. Karpov vs A Chernin |
| 0-1 | 56 |
1992 |
30', Tilburg2.33 ;CBM 32 | D10 Queen's Gambit Declined Slav |
| 22. Karpov vs Salov |
| 1-0 | 57 |
1993 |
Wijk aan Zee 56/409 [Karpov,An | D10 Queen's Gambit Declined Slav |
| 23. Karpov vs Kramnik |
| ½-½ | 11 |
1993 |
07, Dortmund ;CBM 35 | D12 Queen's Gambit Declined Slav |
| 24. Karpov vs Anand |
| ½-½ | 46 |
1993 |
Monaco | D19 Queen's Gambit Declined Slav, Dutch |
| 25. Karpov vs B Ivanovic |
| 1-0 | 22 |
1993 |
Moscow blitz | D10 Queen's Gambit Declined Slav |
