| Game |
| Result | Moves |
Year |
Event/Locale | Opening |
| 1. Karpov vs Maksimov |
 | 1-0 | 60 |
1961 |
Magnitogorsk | E81 King's Indian, Samisch |
| 2. Karpov vs M Dvoretsky |
| 1-0 | 46 |
1967 |
04, Moscow | E81 King's Indian, Samisch |
| 3. Karpov vs Adorjan |
| 0-1 | 41 |
1969 |
Budapest tt-jr (01) | E64 King's Indian, Fianchetto, Yugoslav System |
| 4. Karpov vs Rashkovsky |
| 1-0 | 70 |
1970 |
08, Kuibyshev | E62 King's Indian, Fianchetto |
| 5. Karpov vs Wittman |
| 1-0 | 25 |
1971 |
08, Mayaguez tt-stud | E62 King's Indian, Fianchetto |
| 6. Karpov vs Sax |
| 1-0 | 42 |
1973 |
08, Budapest | E64 King's Indian, Fianchetto, Yugoslav System |
| 7. Karpov vs Rashkovsky |
| 1-0 | 54 |
1973 |
URS-ch41 Moscow ;URS-ch | E61 King's Indian |
| 8. Karpov vs Spassky |
| 1-0 | 55 |
1974 |
Leningrad csf ;CAND | E91 King's Indian |
| 9. Karpov vs Spassky |
| 1-0 | 55 |
1974 |
1/2, ct, Leningrad | E91 King's Indian |
| 10. Karpov vs J Barle |
| 1-0 | 24 |
1975 |
05, Portoroz/Ljubljana | E81 King's Indian, Samisch |
| 11. Karpov vs Falcon |
| 1-0 | 24 |
1976 |
Spanien | E87 King's Indian, Samisch, Orthodox |
| 12. Karpov vs J Diez del Corral |
| 1-0 | 100 |
1976 |
04, Montilla-Moriles | E87 King's Indian, Samisch, Orthodox |
| 13. Karpov vs Velimirovic |
| 1-0 | 67 |
1976 |
It, Skopje | E87 King's Indian, Samisch, Orthodox |
| 14. Karpov vs R Holmes |
| 1-0 | 57 |
1977 |
London | E83 King's Indian, Samisch |
| 15. Karpov vs N Benjamin |
| 1-0 | 40 |
1977 |
Lloyd's bank jr. | E62 King's Indian, Fianchetto |
| 16. Karpov vs Kavalek |
| ½-½ | 18 |
1977 |
08, Tilburg ;MCL 04 | E62 King's Indian, Fianchetto |
| 17. Karpov vs Ermenkov |
| ½-½ | 45 |
1980 |
Ol, Malta 30/705 | E67 King's Indian, Fianchetto |
| 18. Karpov vs Quinteros |
| 1-0 | 41 |
1980 |
12, Malta ol | E92 King's Indian |
| 19. Karpov vs Ermenkov |
| ½-½ | 45 |
1980 |
Malta | E67 King's Indian, Fianchetto |
| 20. Karpov vs Balashov |
| 1-0 | 41 |
1981 |
Moscow INT | E69 King's Indian, Fianchetto, Classical Main line |
| 21. Karpov vs Timman |
| 1-0 | 71 |
1986 |
Bugojno | E60 King's Indian Defense |
| 22. Karpov vs Kasparov |
| ½-½ | 35 |
1986 |
Karpov-Kasparov World Championship Rematch | E60 King's Indian Defense |
| 23. Karpov vs Kasparov |
| ½-½ | 40 |
1986 |
Karpov-Kasparov World Championship Rematch | E60 King's Indian Defense |
| 24. Karpov vs Kasparov |
| ½-½ | 30 |
1987 |
Karpov-Kasparov World Championship Match | E60 King's Indian Defense |
| 25. Karpov vs Van der Wiel |
| ½-½ | 61 |
1987 |
van der Wiel,J, Bruxelles 43/762 | E98 King's Indian, Orthodox, Taimanov, 9.Ne1 |
