| Game |
| Result | Moves |
Year |
Event/Locale | Opening |
| 1. F Caruana vs E Safarli |
| ½-½ | 22 |
2006 |
4th Young Stars of the World | C95 Ruy Lopez, Closed, Breyer |
| 2. F Caruana vs B Roktim |
| 1-0 | 57 |
2006 |
XXIV Andorra Open | C92 Ruy Lopez, Closed |
| 3. F Caruana vs H Banikas |
| ½-½ | 56 |
2007 |
European Team Chess Championships | C92 Ruy Lopez, Closed |
| 4. F Caruana vs S Atalik |
| ½-½ | 57 |
2007 |
European Team Chess Championships | C92 Ruy Lopez, Closed |
| 5. F Caruana vs Adams |
 | 0-1 | 33 |
2007 |
5th Gibraltar Chess Festival | C88 Ruy Lopez |
| 6. F Caruana vs Karpov |
| ½-½ | 43 |
2008 |
Cap d'Agde | C92 Ruy Lopez, Closed |
| 7. F Caruana vs V Aveskulov |
| ½-½ | 29 |
2008 |
European Individual Championship | C96 Ruy Lopez, Closed |
| 8. F Caruana vs Karpov |
| 0-1 | 67 |
2008 |
Cap d'Agde | C92 Ruy Lopez, Closed |
| 9. F Caruana vs G Sargissian |
| 0-1 | 53 |
2008 |
Ruy Lopez Chess Festival | C89 Ruy Lopez, Marshall |
| 10. F Caruana vs W Kobese |
| ½-½ | 33 |
2008 |
2008 Olympiad | C99 Ruy Lopez, Closed, Chigorin, 12...cd |
| 11. F Caruana vs Yusupov |
| ½-½ | 19 |
2008 |
NH Chess | C72 Ruy Lopez, Modern Steinitz Defense, 5.O-O |
| 12. F Caruana vs Stefansson |
| ½-½ | 51 |
2008 |
Reykjavik Open | C78 Ruy Lopez |
| 13. F Caruana vs Korchnoi |
| 1-0 | 28 |
2008 |
2008 Olympiad | C77 Ruy Lopez |
| 14. F Caruana vs Korchnoi |
| 1-0 | 63 |
2008 |
NH Chess | C80 Ruy Lopez, Open |
| 15. F Caruana vs Negi |
| 1-0 | 61 |
2008 |
Corus (Group C) | C89 Ruy Lopez, Marshall |
| 16. F Caruana vs Karpov |
| 0-1 | 66 |
2008 |
Cap d'Agde | C92 Ruy Lopez, Closed |
| 17. F Caruana vs H Stevic |
| 1-0 | 76 |
2008 |
European Individual Championship | C95 Ruy Lopez, Closed, Breyer |
| 18. F Caruana vs M Van der Werf |
| 1-0 | 27 |
2008 |
Corus (Group C) | C90 Ruy Lopez, Closed |
| 19. F Caruana vs Beliavsky |
| ½-½ | 42 |
2009 |
Rising Stars vs Experience | C91 Ruy Lopez, Closed |
| 20. F Caruana vs Mecking |
| 1-0 | 49 |
2009 |
Corus (Group B) | C99 Ruy Lopez, Closed, Chigorin, 12...cd |
| 21. F Caruana vs A Smirnov |
| 1-0 | 44 |
2009 |
Russian Team Championship | C60 Ruy Lopez |
| 22. F Caruana vs M Klenburg |
| 1-0 | 46 |
2009 |
10th European Individual Championship | C99 Ruy Lopez, Closed, Chigorin, 12...cd |
| 23. F Caruana vs J Werle |
| 1-0 | 40 |
2009 |
Corus (Group B) | C84 Ruy Lopez, Closed |
| 24. F Caruana vs P H Nielsen |
| ½-½ | 60 |
2009 |
Rising Stars vs Experience | C64 Ruy Lopez, Classical |
| 25. F Caruana vs Navara |
| 1-0 | 44 |
2009 |
Corus (Group B) | C92 Ruy Lopez, Closed |
